Professional Details

Work Experience: 11 Years

Membership: Society of Biotechnology (India) Chapter

Orcid ID: 0000-0002-8708-9807

Contact Details

Phone number: 9994071533

Email Official:

Email Personal: saranprp@gmail.com

Research – Major Research Areas

  • Native Medicine and Marine Pharmacology

Research – Clinical Trials / Funded Projects

  •  DBT, Govt. of India-on going

Research – List of Publications

  • Venkataprasanna KS, Prakash J, Vignesh S, Bharath G, Manigandan V, Fawzi B, Sahabudeen S, Saravanan R, Devanand GV. (2019). Fabrication of chitosan/PVA/GO/CuO patch for potential wound healing application. Int J Biol Macromole. (Aceppted) (IF-3.9)
  • Velusamy A, Manigandan V, Selvakumar M, Rathinam A, Saravanan R, Umamaheswari S & Arivalagan P. (2019). Metabolite profiling, molecular docking and in vitro anticancer potential of marine ascidian Didmnum sp. Proces. Biochem, (online). (IF-2.61)
  • ManigandanV, Velusamy A, Rubanya P, Karthik R, Karthi S, Sri Ramkumar V, Umamaheswari S, Saravanan R & Arivalagan P. (2019). Antioxidant, anticoagulant and mosquitocidal properties of water soluble polysaccharides (WSPs) from Indian seaweeds. Proces. Biochem, 84: 196-204. (IF-2.61)
  • Arumugam V, Manigandan V, Saravanan N, Saravanan R, Karthi S, Umamahesheswari S & Sathishkumar P. (2019). Tunicates as a biocontrol tool for larvicides acute toxicity of Zika virus vector Aedes aegypti. 3 Biotech, 9: 172-178. (IF-1.4)
  • Malar S, Manigandan V, Velusamy A, Geetha N, Nishakavya S, Selvakumar M, Saravanan R, Rathinam A, & Arivalagan P. (2019). Green synthesis and characterization of titanium dioxide nanoparticles (TiO2 NPs) using Sesbania grandiflora and evaluation of toxicity in zebrafish embryos. Proces. Biochem, 80: 197-202. (IF-2.61)
  • Velusamy A, Manigandan V, Karthik R, Saravanan R, Satheesh Kumar P, & Umamaheswari S. (2019). Purification, characterization and antibacterial properties of peptide from marine ascidian Didemnum sp. Int. J. Pep. Res. Ther, (Online journal. 1-8) (IF-1.13)
  • Karthik R, Manigandan V, Ebenezar KK, Kavitha M, Saravanan R. (2019). Structural characterization, teratogenicity and in vitro avian antimicrobial activity of posterior salivary gland (PSG) toxin from cuttlefish, Sepia prashadi. Int J Biol Macromole. 124: 1145-1155. (IF-3.9)
  • Manigandan V, Nataraj J, Karthik R, Manivasagam T, Saravanan R, Thenmozhi, JA, Essa MM & Guillemin GJ. (2018). Low molecular weight sulfated chitosan: Neuroprotective effect on rotenone-induced in vitro Parkinson’s Disease. Neurotox. Resear, 35(3): 505-515. (IF-3.53)
  • Velusamy A, Manigandan V, Saravanan R, & Umamaheswari S. (2017). Bioactive peptides from Marine Ascidians and future drug development-A review. Int. J. Pep. Resear. Therap. 1: 1-6 (IF-0.94)
  • Karthik R, Manigandan V & Saravanan R. (2017). Toxicity, teratogenicity and antibacterial activity of posterior salivary gland (PSG) toxin from the cuttlefish Sepia pharaonis, Ehrenberg (1831). J. Chromato.B, 1064:28-35. (IF-2.61)
  • Meera M, Ruckmani A, Saravanan R& Lakshimipathy prabhu R. (2017). Anti-inflammatory effect of ethanolic extract of spine, skin and rind of Jack fruit peel – A comparative study. Nat. Prod. Res., 31(22): 1-5 (IF-1.8)
  • Karthik R, Manigandan V, Ebenezar KK, R, Vijayashree R & Saravanan R. (2017). In vitro and in vivo anticancer activity of posterior salivary gland toxin from the cuttlefish Sepia pharaonis, Ehrenberg (1831). Chem.Biol.Inter., 272:10-20. (IF-3.14)
  • Karthik R, Manigandan V, Sheeba R, Saravanan R & Rajesh RP. (2016). Structural characterization and comparative biomedical properties of phloroglucinol from Indian brown seaweeds. J Appl. Phycol., 28: 3561-3573. (IF-2.65)
  • Karthik R, Manigandan V, Saravanan R, Rajesh RP & Baby C. (2016). Structural characterization and in vitro biomedical activities of sulfated chitosan from Sepia pharaonis. Int J Biol Macromole., 84: 319-328. (IF-3.67)
  • Manigandan V, Karthik R & Saravanan R. (2015). Marine carbohydrate based therapeutics for Alzheimer disease – Mini review. J Neurol and Neuroscie., (special issue): 1-6.
  • Karthik R, Saravanan R, Ebenezar KK & Sivamalai T. (2014). Isolation, purification, and characterization of avian antimicrobial glycopeptide from the posterior salivary gland of Sepia pharaonis. Appl Biochem Biotechnol., 175(3): 1507-1518. (IF-1.73)
  • Subhapradha N, Saravanan R, Ramasamy P, Shanmugam V, Srinivasan A &
    Shanmugam A. (2014). Hepatoprotective effect of β-Chitosan from gladius of Sepioteuthis lessoniana against carbon tetrachloride-induced oxidative stress in Wistar rats. Appl Biochem Biotechnol., 172: 9-20. (IF-1.73)
  • Vidhyanandhini R, Saravanan R, Vairamani S & Shanmugam A. (2014). The anticoagulant activity and structural characterization of fractionated and purified glycosaminoglycans from venerid clam Meretrix casta (Chemnitz). J Liquid Chrom Relat Tech., 37: 917-929. (IF-0.63)
  • Sudharsan S, Seedevi P, Saravanan R, Vairamani S, Vasanthkumar S, Srinivasan A & Shanmugam A. (2013). Isolation, characterization and molecular weight determination of collagen from marine sponge Spirastrella inconstans (Dendy). Afri J Biotechnol., 12(5): 504-511. (IF-0.57)
  • Saravanan R, Ramasamy P, Sudharsan S, Vairamani S & Shanmugam A. (2013). Protective effect of glycosaminoglycans from meretrix meretrix (gmelin) against isoproterenol – induced myocardial infarction in male wistar rats. Amer J Adv Drug Del., 1: 56-65. (IF-0.64)
  • Saravanan R, Ebenezar KK, Rajasekaran S & Thamaraiselvan R. (2013). Isolation, characterization and anticoagulant activity of sulfated polysaccharides from brown algae Sargasam wightii Greville. J Biol Sci., 13(4): 283-287.
  • Subhapradha N, Suman S, Ramasamy P, Saravanan R, Shanmugam V, Srinivasan A & Shanmugam A. (2013). Anticoagulant and antioxidant activity of sulfated chitosan from the shell of donacid clam Donax scortum (Linnaeus, 1758). Int J Nutri Pharmacol Neur Dis., 3(1): 39-45.
  • Saravanan R, Shanmugam A & Rajkumar D. (2012). Preventive effect of glycosaminoglycans from Amussium pleuronectus (Linne) on biomolecules, lactate dehydrogenase-isoenzyme and electrocardiographic patterns in isoproterenol-induced myocardial infarction in Wistar rats. Indian J Pharmacol., 44(5): 602-606. (IF-0.69)
  • Shanmugam A, Subhapradha N, Suman S, Ramasamy P, Saravanan R, Shanmugam V & Srinivasan A. (2012). Characterization of biopolymer chitosan from the shell of donacid clam Donax scortum (Linnaeus, 1758) and its antioxidant activity. Int J Pharmacy Pharmaceut Sci., 4(2): 460-465.
  • Revathi M, Saravanan R & Shanmugam A. (2012). Extraction of chitin from the cuttlebone of Sepiella inermis Orbigny, 1848 and production, purification and characterization of chitinase from Vibrio sp. using head waste of shirmp Metapenaeus dobsonii (Miers, 1878). Advan Biosci Biotechnol., 3:392-397.
  • Saravanan R & Shanmugam A, (2011). Is isolation and characterization of heparan sulfate from marine scallop Amussium pleuronectus (Linne) an alternative source of heparin?!! Carbohyd Poly., 86 (2), 1082-1084. (IF-4.07)
  • Saravanan R, Arulraj S & Shanmugam A. (2011). Identification of two mud crab species (genus Scylla) using restriction fragment length polymorphism. Cur Sci., 101(6): 739-740. (IF-0.92)
  • Ramasamy P, Barwin Vino A, Saravanan R, Subhapradha N, Shanmugam V &
    Shanmugam A. (2011). Screening of antimicrobial potential of polysaccharide from cuttlebone and methanolic extract from body tissue of Sepia prashadi Winkworth, 1936. Asian Paci J Trop Biomed., S243-S247. (IF-1.17)
  • Shanmugam A, Ramasamy P, Mukesh Kumar Bharti, Saravanan R, Subhapradha N, Vairamani S, & Jayalakshmi K. (2011). Isolation and characterization of collagen from the skin of Sepia pharaonis (Ehrenberg, 1831). Int J Cur Res., 3(6), 107-111.
  • Sudharsan S, Saravanan R, Shanmugam A, Vairamani S, Mohan Kumar R, Menaga S, & Ramesh N. (2011). Isolation, characterization of octadecanoic acid from the etyl acetate root extract of Trigoellafoneum graecum L. by using hydropnics method. Bioterr Biodefen., 2(1): 1-4.
  • Saravanan R & Shanmugam A. (2010). Isolation and characterization of low molecular weight glycosaminoglycans from marine mollusc Amussium pleuronectus (Linne) using chromatrography. Appl Biochem Biotechnol., 160, 791-799. (IF-1.73)
  • Saravanan R & Shanmugam A. (2010). Preventive effect of low molecular weight glycosaminoglycan from Amussium pleuronectus (Linne) on oxidative injury and cellular abnormalities in isoproterenol-induced cardiotoxicity in Wistar rats. Appl Biochem Biotechnol., 162, 43-51. (IF-1.73)
  • Saravanan R, Vairamani S & Shanmugam A. (2010). Glycosaminoglycans from marine clam Meretrix meretrix (Linne.) are an anticoagulant. Prep Biochem Biotechnol., 40, 305-315. (IF-1.01)
  • Saravanan R, Sambasivam S, Shanmugam A, Tamilvanan T, Sathishkumar D & Nazeer RA. (2009). Isolation, purification and biochemical characterization of conotoxin from Conus figulinus Linneaus (1758). Indian J Biotechnol., 8, 266-271. (IF-0.68)
  • Saravanan R, Shanmugam A, Preethi Ashok, Sathishkumar D, Anand K, Amitesh Suman & Devodass FR. (2009). Studies on isolation and partial purification of lysozyme from the egg white of lovebird (Agapornis species). Afr J Biotechnol., 8(1), 107-109. (IF-0.57)
  • Saravanan R, Pavanidevi V, Shanmugam A & Sathishkumar D. (2007). Isolation and partial purification of extracellular enzyme (1,3)-β-D glucanase from Trichoderma reesei (3929). Biotechnol., 6(3), 440-443.”

Patents : 3

Reviewer for Scientific Journals / Research Proposals

  • Carbohydrate Polymers, Process of Biochemistry, Apllied Biotechmistry and Biotechnology

Research Topics

  • Structural Biology, Glycobiology, Polymers/peptides/toxins from Marine Species – Marine Pharmacology
  • 18 Presented/4 poster/3 Resource Person

Major Awards/Honours and Fellowships

  • ICMR-SRF
Research and Publication

Research – Major Research Areas

  • Native Medicine and Marine Pharmacology

Research – Clinical Trials / Funded Projects

  •  DBT, Govt. of India-on going

Research – List of Publications

  • Venkataprasanna KS, Prakash J, Vignesh S, Bharath G, Manigandan V, Fawzi B, Sahabudeen S, Saravanan R, Devanand GV. (2019). Fabrication of chitosan/PVA/GO/CuO patch for potential wound healing application. Int J Biol Macromole. (Aceppted) (IF-3.9)
  • Velusamy A, Manigandan V, Selvakumar M, Rathinam A, Saravanan R, Umamaheswari S & Arivalagan P. (2019). Metabolite profiling, molecular docking and in vitro anticancer potential of marine ascidian Didmnum sp. Proces. Biochem, (online). (IF-2.61)
  • ManigandanV, Velusamy A, Rubanya P, Karthik R, Karthi S, Sri Ramkumar V, Umamaheswari S, Saravanan R & Arivalagan P. (2019). Antioxidant, anticoagulant and mosquitocidal properties of water soluble polysaccharides (WSPs) from Indian seaweeds. Proces. Biochem, 84: 196-204. (IF-2.61)
  • Arumugam V, Manigandan V, Saravanan N, Saravanan R, Karthi S, Umamahesheswari S & Sathishkumar P. (2019). Tunicates as a biocontrol tool for larvicides acute toxicity of Zika virus vector Aedes aegypti. 3 Biotech, 9: 172-178. (IF-1.4)
  • Malar S, Manigandan V, Velusamy A, Geetha N, Nishakavya S, Selvakumar M, Saravanan R, Rathinam A, & Arivalagan P. (2019). Green synthesis and characterization of titanium dioxide nanoparticles (TiO2 NPs) using Sesbania grandiflora and evaluation of toxicity in zebrafish embryos. Proces. Biochem, 80: 197-202. (IF-2.61)
  • Velusamy A, Manigandan V, Karthik R, Saravanan R, Satheesh Kumar P, & Umamaheswari S. (2019). Purification, characterization and antibacterial properties of peptide from marine ascidian Didemnum sp. Int. J. Pep. Res. Ther, (Online journal. 1-8) (IF-1.13)
  • Karthik R, Manigandan V, Ebenezar KK, Kavitha M, Saravanan R. (2019). Structural characterization, teratogenicity and in vitro avian antimicrobial activity of posterior salivary gland (PSG) toxin from cuttlefish, Sepia prashadi. Int J Biol Macromole. 124: 1145-1155. (IF-3.9)
  • Manigandan V, Nataraj J, Karthik R, Manivasagam T, Saravanan R, Thenmozhi, JA, Essa MM & Guillemin GJ. (2018). Low molecular weight sulfated chitosan: Neuroprotective effect on rotenone-induced in vitro Parkinson’s Disease. Neurotox. Resear, 35(3): 505-515. (IF-3.53)
  • Velusamy A, Manigandan V, Saravanan R, & Umamaheswari S. (2017). Bioactive peptides from Marine Ascidians and future drug development-A review. Int. J. Pep. Resear. Therap. 1: 1-6 (IF-0.94)
  • Karthik R, Manigandan V & Saravanan R. (2017). Toxicity, teratogenicity and antibacterial activity of posterior salivary gland (PSG) toxin from the cuttlefish Sepia pharaonis, Ehrenberg (1831). J. Chromato.B, 1064:28-35. (IF-2.61)
  • Meera M, Ruckmani A, Saravanan R& Lakshimipathy prabhu R. (2017). Anti-inflammatory effect of ethanolic extract of spine, skin and rind of Jack fruit peel – A comparative study. Nat. Prod. Res., 31(22): 1-5 (IF-1.8)
  • Karthik R, Manigandan V, Ebenezar KK, R, Vijayashree R & Saravanan R. (2017). In vitro and in vivo anticancer activity of posterior salivary gland toxin from the cuttlefish Sepia pharaonis, Ehrenberg (1831). Chem.Biol.Inter., 272:10-20. (IF-3.14)
  • Karthik R, Manigandan V, Sheeba R, Saravanan R & Rajesh RP. (2016). Structural characterization and comparative biomedical properties of phloroglucinol from Indian brown seaweeds. J Appl. Phycol., 28: 3561-3573. (IF-2.65)
  • Karthik R, Manigandan V, Saravanan R, Rajesh RP & Baby C. (2016). Structural characterization and in vitro biomedical activities of sulfated chitosan from Sepia pharaonis. Int J Biol Macromole., 84: 319-328. (IF-3.67)
  • Manigandan V, Karthik R & Saravanan R. (2015). Marine carbohydrate based therapeutics for Alzheimer disease – Mini review. J Neurol and Neuroscie., (special issue): 1-6.
  • Karthik R, Saravanan R, Ebenezar KK & Sivamalai T. (2014). Isolation, purification, and characterization of avian antimicrobial glycopeptide from the posterior salivary gland of Sepia pharaonis. Appl Biochem Biotechnol., 175(3): 1507-1518. (IF-1.73)
  • Subhapradha N, Saravanan R, Ramasamy P, Shanmugam V, Srinivasan A &
    Shanmugam A. (2014). Hepatoprotective effect of β-Chitosan from gladius of Sepioteuthis lessoniana against carbon tetrachloride-induced oxidative stress in Wistar rats. Appl Biochem Biotechnol., 172: 9-20. (IF-1.73)
  • Vidhyanandhini R, Saravanan R, Vairamani S & Shanmugam A. (2014). The anticoagulant activity and structural characterization of fractionated and purified glycosaminoglycans from venerid clam Meretrix casta (Chemnitz). J Liquid Chrom Relat Tech., 37: 917-929. (IF-0.63)
  • Sudharsan S, Seedevi P, Saravanan R, Vairamani S, Vasanthkumar S, Srinivasan A & Shanmugam A. (2013). Isolation, characterization and molecular weight determination of collagen from marine sponge Spirastrella inconstans (Dendy). Afri J Biotechnol., 12(5): 504-511. (IF-0.57)
  • Saravanan R, Ramasamy P, Sudharsan S, Vairamani S & Shanmugam A. (2013). Protective effect of glycosaminoglycans from meretrix meretrix (gmelin) against isoproterenol – induced myocardial infarction in male wistar rats. Amer J Adv Drug Del., 1: 56-65. (IF-0.64)
  • Saravanan R, Ebenezar KK, Rajasekaran S & Thamaraiselvan R. (2013). Isolation, characterization and anticoagulant activity of sulfated polysaccharides from brown algae Sargasam wightii Greville. J Biol Sci., 13(4): 283-287.
  • Subhapradha N, Suman S, Ramasamy P, Saravanan R, Shanmugam V, Srinivasan A & Shanmugam A. (2013). Anticoagulant and antioxidant activity of sulfated chitosan from the shell of donacid clam Donax scortum (Linnaeus, 1758). Int J Nutri Pharmacol Neur Dis., 3(1): 39-45.
  • Saravanan R, Shanmugam A & Rajkumar D. (2012). Preventive effect of glycosaminoglycans from Amussium pleuronectus (Linne) on biomolecules, lactate dehydrogenase-isoenzyme and electrocardiographic patterns in isoproterenol-induced myocardial infarction in Wistar rats. Indian J Pharmacol., 44(5): 602-606. (IF-0.69)
  • Shanmugam A, Subhapradha N, Suman S, Ramasamy P, Saravanan R, Shanmugam V & Srinivasan A. (2012). Characterization of biopolymer chitosan from the shell of donacid clam Donax scortum (Linnaeus, 1758) and its antioxidant activity. Int J Pharmacy Pharmaceut Sci., 4(2): 460-465.
  • Revathi M, Saravanan R & Shanmugam A. (2012). Extraction of chitin from the cuttlebone of Sepiella inermis Orbigny, 1848 and production, purification and characterization of chitinase from Vibrio sp. using head waste of shirmp Metapenaeus dobsonii (Miers, 1878). Advan Biosci Biotechnol., 3:392-397.
  • Saravanan R & Shanmugam A, (2011). Is isolation and characterization of heparan sulfate from marine scallop Amussium pleuronectus (Linne) an alternative source of heparin?!! Carbohyd Poly., 86 (2), 1082-1084. (IF-4.07)
  • Saravanan R, Arulraj S & Shanmugam A. (2011). Identification of two mud crab species (genus Scylla) using restriction fragment length polymorphism. Cur Sci., 101(6): 739-740. (IF-0.92)
  • Ramasamy P, Barwin Vino A, Saravanan R, Subhapradha N, Shanmugam V &
    Shanmugam A. (2011). Screening of antimicrobial potential of polysaccharide from cuttlebone and methanolic extract from body tissue of Sepia prashadi Winkworth, 1936. Asian Paci J Trop Biomed., S243-S247. (IF-1.17)
  • Shanmugam A, Ramasamy P, Mukesh Kumar Bharti, Saravanan R, Subhapradha N, Vairamani S, & Jayalakshmi K. (2011). Isolation and characterization of collagen from the skin of Sepia pharaonis (Ehrenberg, 1831). Int J Cur Res., 3(6), 107-111.
  • Sudharsan S, Saravanan R, Shanmugam A, Vairamani S, Mohan Kumar R, Menaga S, & Ramesh N. (2011). Isolation, characterization of octadecanoic acid from the etyl acetate root extract of Trigoellafoneum graecum L. by using hydropnics method. Bioterr Biodefen., 2(1): 1-4.
  • Saravanan R & Shanmugam A. (2010). Isolation and characterization of low molecular weight glycosaminoglycans from marine mollusc Amussium pleuronectus (Linne) using chromatrography. Appl Biochem Biotechnol., 160, 791-799. (IF-1.73)
  • Saravanan R & Shanmugam A. (2010). Preventive effect of low molecular weight glycosaminoglycan from Amussium pleuronectus (Linne) on oxidative injury and cellular abnormalities in isoproterenol-induced cardiotoxicity in Wistar rats. Appl Biochem Biotechnol., 162, 43-51. (IF-1.73)
  • Saravanan R, Vairamani S & Shanmugam A. (2010). Glycosaminoglycans from marine clam Meretrix meretrix (Linne.) are an anticoagulant. Prep Biochem Biotechnol., 40, 305-315. (IF-1.01)
  • Saravanan R, Sambasivam S, Shanmugam A, Tamilvanan T, Sathishkumar D & Nazeer RA. (2009). Isolation, purification and biochemical characterization of conotoxin from Conus figulinus Linneaus (1758). Indian J Biotechnol., 8, 266-271. (IF-0.68)
  • Saravanan R, Shanmugam A, Preethi Ashok, Sathishkumar D, Anand K, Amitesh Suman & Devodass FR. (2009). Studies on isolation and partial purification of lysozyme from the egg white of lovebird (Agapornis species). Afr J Biotechnol., 8(1), 107-109. (IF-0.57)
  • Saravanan R, Pavanidevi V, Shanmugam A & Sathishkumar D. (2007). Isolation and partial purification of extracellular enzyme (1,3)-β-D glucanase from Trichoderma reesei (3929). Biotechnol., 6(3), 440-443.”

Patents : 3

Reviewer for Scientific Journals / Research Proposals

  • Carbohydrate Polymers, Process of Biochemistry, Apllied Biotechmistry and Biotechnology

Research Topics

  • Structural Biology, Glycobiology, Polymers/peptides/toxins from Marine Species – Marine Pharmacology
Conferences - Papers presented
Awards, Achievements & Fellowships

© 2020 Chettinad Academy