Professional Details
Work Experience: 10 years afer PhD and two years after MSc
Membership: Lifemember -Indian Association of Biomedical Scientists (IABMS)
Examinership: 8 years
Contact Details
Phone number: 9962527952
Email Official: gowtham.genetics@chettinadhealthcity.com
Email Personal: gowtham_phd@yahoo.com
Research – Major Research Areas
- Genetic Polymorphism assiciated with disease,Angiogenesis,Applied Microbiology
Research – Clinical Trials / Funded Projects
- Received EMR Project from DST SERB (Cost:47 Lakhs)
Research – List of Publications
- Sindhu Varghese,S. Gowtham Kumar. APrevalence of micro albuminuria and diagnostic accuracy of urine dipstick for the screening of diabetic nephropathy in type 2 diabetes patients. Biocatalysis and Agricultural Biotechnology 21 (2019) 101316.
- Sindhu Varghese,S. Gowtham Kumar. Association between genetic variants of NOS3, TGF-β
and susceptibility of diabetic nephropathy: A meta-analysis.Meta Gene 21:100573 ,April 2019.
DOI: 10.1016/j.mgene.2019.100573 - Identification of potential inhibitors for Penicillin binding protein (PBP) from Staphylococcus aureus. L Kulanthaivel, J Jeyaraman, A Biswas, Gowtham Kumar Subbaraj, S Santhoshkumar,Bioinformation 14 (9), 471-476.
V. Ramakrishnan, R. S. Akram Husain, S. Gowtham Kumar. An overview of rare genetic
disorders and recent diagnostic approaches, Saudi Journal for Health Sciences (2016) 5, 105-
117. - Langeswaran K, Gowthamkumar S, Vijayaprakash S, Revathy R, Balasubramanian MP.
Influence of limonin on Wnt signalling molecule in HepG2 cell lines. J Nat Sc Biol Med (4):126-
33;2013. (Citation:27). - Kulanthaivel Langeswaran, Rajendran Revathy, Subbaraj Gowtham Kumar, Shanmugam
Vijayaprakash, Maruthaiveeran Periyasamy Balasubramanian. Kaempferol ameliorates aflatoxin
B1 (AFB1) induced hepatocellular carcinoma through modifying metabolizing enzymes,
membrane bound ATPases and mitochondrial TCA cycle enzymes. Asian Pacific Journal of
Tropical Biomedicine,S165-3S1659;2012. (Citation:15). - Peranandam Tamilselvan, Kulanthaivel Langeswaran, Shanmugam Vijayaprakash,
Subbaraj Gowtham kumar,Rajendran Revathy, Maruthaiveeran Periyaswamy
Balasubramanian. Efficiency of lycopene against reproductive and developmental toxicity of
Bisphenol A in male Sprague Dawley rats, Biomedicine & Preventive Nutrition, 4, (4), 491-498;
2014. - V Ramakrishnan, S Gowtham Kumar, Radha Pandiyan. Klinefelter Syndrome and its association
with Male Infertility. As Pac JReprod, 3(1): 77-79; 2014 (Citation:1). - R.Revathy, K. Langeswaran, S. Gowtham Kumar, S.Vijayaprakash, P.Tamilselvan, M P
Balasubramanian. Anti-infertility significance of aqueous extract of Ipomoea batatas (L.) Lam.
against exposure of bisphenol A (BPA) promoted testicular toxicity in male Sprague Dawley rats,
As Pac JReprod, 2(4), 263-271;2013 (Elsevier)(Citation:3). - JayaramanJagadeesan, Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar,
Maruthaiveeran Periyaswamy Balasubramanian. Diosgenin exhibits beneficial efficiency on
human mammary carcinoma cell line MCF-7 and against N- nitroso-N- methylurea (NMU)
induced experimental mammary carcinoma. Biomedicine & Preventive Nutrition, 3(4), 381-388;
2013 (Elsevier) (Citation:2). - Shanmugam Vijayaprakash, Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar, Rajendran
Revathy, Maruthaiveeran Periyasamy Balasubramanian.Nephro-protective significance of
kaempferol on mercuric chloride induced toxicity in Wistar albino rats. Biomedicine & Aging
Pathology, 3;(3) 119-124; 2013 (Citation:6). - Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar, Srinivasan Perumal, Rajendran Revathy,
Maruthaiveeran Periyasamy Balasubramaniam. Limonin – A citrus limonoid, establish anticancer
potential by stabilizing lipid peroxidation and antioxidant status againstN- nitrosodiethylamine
induced experimental hepatocellular carcinoma. Biomedicine & Preventive Nutrition, 3(2),
165-171;2013 (Citation:5). - Gowtham kumar S, Ramakrishnan V,Madhusudhanan N, and Balasubramanian MP. 2011.
Antioxidant activity of Allyl isothiocyanate [ AITC] against N -nitrosodiethylamine induced
experimental liver carcinogenesis, Journal of Pharmacy Research. 4-(10). - S. Gowtham Kumar, V.Ramakrishnan, N.Madhusudhanan, G.Thiyagarajan,
K.Langeswaran, and M.P. Balasubramanian. 2011. p53 and caspase 3 gene expression
potential of allyl isothiocyanate evaluated on human hepatoma cell line (HepG2). International
journal of biological & pharmaceutical research. 2(1); 19 – 26. - Ramakrishnan V, Gowtham kumar S and Madhusudhanan. Nov- 2011. N Genetic basis of
coronary artery disease and its risk factors, Journal of Pharmacy Research. - Madhusudhanan N, Lakshmi T, Gowtham Kumar S ,Ramakrishanan,Venu Gopala Rao Konda,
Anitha Roy and Geetha R.V. Jul-Sep 2011.“ Invitro Antioxidant And Free Radical Scavenging
Activity Of Aqueous And Ethanolic Flower Extract Of Nymphaea Alba ” , Int. J. Drug Dev. & Res.
3(3); 252-258. - V.Ramakrisnan, S. Gowtham Kumar, G.Thiyagarajan N.Madhusudhanan and S Vincent.
2011.The use of cytokinesis-block micronucleus (CBMN) assay to identify DNA damage in
patients with coronary artery disease’ Int JMed Res. 1(2); 111-117. - V.Ramakrishnan, S. Gowtham Kumar, N.Madhusudhanan G.Thiyagarajan,and
S.Govindaraju. 2011. “ Effect of 2-Deoxy- D- Glucose and Cyclophosphamide mediated
modification of induced genetic damage in albino Mice ” International journal of biological &
Pharmaceutical research. 131–138; Impact factor: 0. 92. - V.Ramakrishnan, S. Gowtham kumar and S.Govindaraju. 2011.“ Cytogenetic analysis of
micronuclei, sister chromatid exchange and chromosomal aberrations in pan masala chewers”
International journal of Pharma and Biosciences. 2(3); 01– 13. - Madhusudhanan N, Ruckmani A, Gowtham kumar S, Ramakrishnan Vand
Balasubramanian MP. 2011. “ Invitro cytotoxic activity of berberine on human lung carcinoma
cell line A549” Journal of Pharmacy Research.Vol 4, No 12. - V.Ramakrishnan, G.Thiyagarajan, S.Pulavendran, S.Gowtham Kumar, N.Madhusudhanan and S
Vincent. 2010. ‘Study of Serum Metals and Antioxidant Enzymes in Patients with Coronary
Artery Disease. International Journal of Genetic Engineering and Biotechnology. 1(3); 205 – 216.
Reviewer for Scientific Journals / Research Proposals
- Journal of Applied Pharmaceutical Science (JAPS)
- 10/05/2016 ICMR sponsored National level Seminar on “Recent Advances in Orthopaedic implants
Major Awards/Honours and Fellowships
- UGC-SAPFellowship for meritorious students
Patents – 1
Research and Publication
Research – Major Research Areas
- Genetic Polymorphism assiciated with disease,Angiogenesis,Applied Microbiology
Research – Clinical Trials / Funded Projects
- Received EMR Project from DST SERB (Cost:47 Lakhs)
Research – List of Publications
- Sindhu Varghese,S. Gowtham Kumar. APrevalence of micro albuminuria and diagnostic accuracy of urine dipstick for the screening of diabetic nephropathy in type 2 diabetes patients. Biocatalysis and Agricultural Biotechnology 21 (2019) 101316.
- Sindhu Varghese,S. Gowtham Kumar. Association between genetic variants of NOS3, TGF-β
and susceptibility of diabetic nephropathy: A meta-analysis.Meta Gene 21:100573 ,April 2019.
DOI: 10.1016/j.mgene.2019.100573 - Identification of potential inhibitors for Penicillin binding protein (PBP) from Staphylococcus aureus. L Kulanthaivel, J Jeyaraman, A Biswas, Gowtham Kumar Subbaraj, S Santhoshkumar,Bioinformation 14 (9), 471-476.
V. Ramakrishnan, R. S. Akram Husain, S. Gowtham Kumar. An overview of rare genetic
disorders and recent diagnostic approaches, Saudi Journal for Health Sciences (2016) 5, 105-
117. - Langeswaran K, Gowthamkumar S, Vijayaprakash S, Revathy R, Balasubramanian MP.
Influence of limonin on Wnt signalling molecule in HepG2 cell lines. J Nat Sc Biol Med (4):126-
33;2013. (Citation:27). - Kulanthaivel Langeswaran, Rajendran Revathy, Subbaraj Gowtham Kumar, Shanmugam
Vijayaprakash, Maruthaiveeran Periyasamy Balasubramanian. Kaempferol ameliorates aflatoxin
B1 (AFB1) induced hepatocellular carcinoma through modifying metabolizing enzymes,
membrane bound ATPases and mitochondrial TCA cycle enzymes. Asian Pacific Journal of
Tropical Biomedicine,S165-3S1659;2012. (Citation:15). - Peranandam Tamilselvan, Kulanthaivel Langeswaran, Shanmugam Vijayaprakash,
Subbaraj Gowtham kumar,Rajendran Revathy, Maruthaiveeran Periyaswamy
Balasubramanian. Efficiency of lycopene against reproductive and developmental toxicity of
Bisphenol A in male Sprague Dawley rats, Biomedicine & Preventive Nutrition, 4, (4), 491-498;
2014. - V Ramakrishnan, S Gowtham Kumar, Radha Pandiyan. Klinefelter Syndrome and its association
with Male Infertility. As Pac JReprod, 3(1): 77-79; 2014 (Citation:1). - R.Revathy, K. Langeswaran, S. Gowtham Kumar, S.Vijayaprakash, P.Tamilselvan, M P
Balasubramanian. Anti-infertility significance of aqueous extract of Ipomoea batatas (L.) Lam.
against exposure of bisphenol A (BPA) promoted testicular toxicity in male Sprague Dawley rats,
As Pac JReprod, 2(4), 263-271;2013 (Elsevier)(Citation:3). - JayaramanJagadeesan, Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar,
Maruthaiveeran Periyaswamy Balasubramanian. Diosgenin exhibits beneficial efficiency on
human mammary carcinoma cell line MCF-7 and against N- nitroso-N- methylurea (NMU)
induced experimental mammary carcinoma. Biomedicine & Preventive Nutrition, 3(4), 381-388;
2013 (Elsevier) (Citation:2). - Shanmugam Vijayaprakash, Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar, Rajendran
Revathy, Maruthaiveeran Periyasamy Balasubramanian.Nephro-protective significance of
kaempferol on mercuric chloride induced toxicity in Wistar albino rats. Biomedicine & Aging
Pathology, 3;(3) 119-124; 2013 (Citation:6). - Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar, Srinivasan Perumal, Rajendran Revathy,
Maruthaiveeran Periyasamy Balasubramaniam. Limonin – A citrus limonoid, establish anticancer
potential by stabilizing lipid peroxidation and antioxidant status againstN- nitrosodiethylamine
induced experimental hepatocellular carcinoma. Biomedicine & Preventive Nutrition, 3(2),
165-171;2013 (Citation:5). - Gowtham kumar S, Ramakrishnan V,Madhusudhanan N, and Balasubramanian MP. 2011.
Antioxidant activity of Allyl isothiocyanate [ AITC] against N -nitrosodiethylamine induced
experimental liver carcinogenesis, Journal of Pharmacy Research. 4-(10). - S. Gowtham Kumar, V.Ramakrishnan, N.Madhusudhanan, G.Thiyagarajan,
K.Langeswaran, and M.P. Balasubramanian. 2011. p53 and caspase 3 gene expression
potential of allyl isothiocyanate evaluated on human hepatoma cell line (HepG2). International
journal of biological & pharmaceutical research. 2(1); 19 – 26. - Ramakrishnan V, Gowtham kumar S and Madhusudhanan. Nov- 2011. N Genetic basis of
coronary artery disease and its risk factors, Journal of Pharmacy Research. - Madhusudhanan N, Lakshmi T, Gowtham Kumar S ,Ramakrishanan,Venu Gopala Rao Konda,
Anitha Roy and Geetha R.V. Jul-Sep 2011.“ Invitro Antioxidant And Free Radical Scavenging
Activity Of Aqueous And Ethanolic Flower Extract Of Nymphaea Alba ” , Int. J. Drug Dev. & Res.
3(3); 252-258. - V.Ramakrisnan, S. Gowtham Kumar, G.Thiyagarajan N.Madhusudhanan and S Vincent.
2011.The use of cytokinesis-block micronucleus (CBMN) assay to identify DNA damage in
patients with coronary artery disease’ Int JMed Res. 1(2); 111-117. - V.Ramakrishnan, S. Gowtham Kumar, N.Madhusudhanan G.Thiyagarajan,and
S.Govindaraju. 2011. “ Effect of 2-Deoxy- D- Glucose and Cyclophosphamide mediated
modification of induced genetic damage in albino Mice ” International journal of biological &
Pharmaceutical research. 131–138; Impact factor: 0. 92. - V.Ramakrishnan, S. Gowtham kumar and S.Govindaraju. 2011.“ Cytogenetic analysis of
micronuclei, sister chromatid exchange and chromosomal aberrations in pan masala chewers”
International journal of Pharma and Biosciences. 2(3); 01– 13. - Madhusudhanan N, Ruckmani A, Gowtham kumar S, Ramakrishnan Vand
Balasubramanian MP. 2011. “ Invitro cytotoxic activity of berberine on human lung carcinoma
cell line A549” Journal of Pharmacy Research.Vol 4, No 12. - V.Ramakrishnan, G.Thiyagarajan, S.Pulavendran, S.Gowtham Kumar, N.Madhusudhanan and S
Vincent. 2010. ‘Study of Serum Metals and Antioxidant Enzymes in Patients with Coronary
Artery Disease. International Journal of Genetic Engineering and Biotechnology. 1(3); 205 – 216.
Reviewer for Scientific Journals / Research Proposals
- Journal of Applied Pharmaceutical Science (JAPS)