Professional Details

Work Experience: 10 years afer PhD and two years after MSc

Membership: Lifemember -Indian Association of Biomedical Scientists (IABMS)

Examinership: 8 years

Contact Details

Phone number: 9962527952

Email Official: gowtham.genetics@chettinadhealthcity.com

Email Personal: gowtham_phd@yahoo.com

Research – Major Research Areas

  • Genetic Polymorphism assiciated with disease,Angiogenesis,Applied Microbiology

Research – Clinical Trials / Funded Projects

  • Received EMR Project from DST SERB (Cost:47 Lakhs)

Research – List of Publications

  • Sindhu Varghese,S. Gowtham Kumar. APrevalence of micro albuminuria and diagnostic accuracy of urine dipstick for the screening of diabetic nephropathy in type 2 diabetes patients.  Biocatalysis and Agricultural Biotechnology 21 (2019) 101316.
  • Sindhu Varghese,S. Gowtham Kumar. Association between genetic variants of NOS3, TGF-β
    and susceptibility of diabetic nephropathy: A meta-analysis.Meta Gene 21:100573 ,April 2019.
    DOI: 10.1016/j.mgene.2019.100573
  • Identification of potential inhibitors for Penicillin binding protein (PBP) from Staphylococcus aureus. L Kulanthaivel, J Jeyaraman, A Biswas, Gowtham Kumar Subbaraj, S Santhoshkumar,Bioinformation 14 (9), 471-476.
    V. Ramakrishnan, R. S. Akram Husain, S. Gowtham Kumar. An overview of rare genetic
    disorders and recent diagnostic approaches, Saudi Journal for Health Sciences (2016) 5, 105-
    117.
  • Langeswaran K, Gowthamkumar S, Vijayaprakash S, Revathy R, Balasubramanian MP.
    Influence of limonin on Wnt signalling molecule in HepG2 cell lines. J Nat Sc Biol Med (4):126-
    33;2013. (Citation:27).
  • Kulanthaivel Langeswaran, Rajendran Revathy, Subbaraj Gowtham Kumar, Shanmugam
    Vijayaprakash, Maruthaiveeran Periyasamy Balasubramanian. Kaempferol ameliorates aflatoxin
    B1 (AFB1) induced hepatocellular carcinoma through modifying metabolizing enzymes,
    membrane bound ATPases and mitochondrial TCA cycle enzymes. Asian Pacific Journal of
    Tropical Biomedicine,S165-3S1659;2012. (Citation:15).
  • Peranandam Tamilselvan, Kulanthaivel Langeswaran, Shanmugam Vijayaprakash,
    Subbaraj Gowtham kumar,Rajendran Revathy, Maruthaiveeran Periyaswamy
    Balasubramanian. Efficiency of lycopene against reproductive and developmental toxicity of
    Bisphenol A in male Sprague Dawley rats, Biomedicine & Preventive Nutrition, 4, (4), 491-498;
    2014.
  • V Ramakrishnan, S Gowtham Kumar, Radha Pandiyan. Klinefelter Syndrome and its association
    with Male Infertility. As Pac JReprod, 3(1): 77-79; 2014 (Citation:1).
  • R.Revathy, K. Langeswaran, S. Gowtham Kumar, S.Vijayaprakash, P.Tamilselvan, M P
    Balasubramanian. Anti-infertility significance of aqueous extract of Ipomoea batatas (L.) Lam.
    against exposure of bisphenol A (BPA) promoted testicular toxicity in male Sprague Dawley rats,
    As Pac JReprod, 2(4), 263-271;2013 (Elsevier)(Citation:3).
  • JayaramanJagadeesan, Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar,
    Maruthaiveeran Periyaswamy Balasubramanian. Diosgenin exhibits beneficial efficiency on
    human mammary carcinoma cell line MCF-7 and against N- nitroso-N- methylurea (NMU)
    induced experimental mammary carcinoma. Biomedicine & Preventive Nutrition, 3(4), 381-388;
    2013 (Elsevier) (Citation:2).
  • Shanmugam Vijayaprakash, Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar, Rajendran
    Revathy, Maruthaiveeran Periyasamy Balasubramanian.Nephro-protective significance of
    kaempferol on mercuric chloride induced toxicity in Wistar albino rats. Biomedicine & Aging
    Pathology, 3;(3) 119-124; 2013 (Citation:6).
  • Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar, Srinivasan Perumal, Rajendran Revathy,
    Maruthaiveeran Periyasamy Balasubramaniam. Limonin – A citrus limonoid, establish anticancer
    potential by stabilizing lipid peroxidation and antioxidant status againstN- nitrosodiethylamine
    induced experimental hepatocellular carcinoma. Biomedicine & Preventive Nutrition, 3(2),
    165-171;2013 (Citation:5).
  • Gowtham kumar S, Ramakrishnan V,Madhusudhanan N, and Balasubramanian MP. 2011.
    Antioxidant activity of Allyl isothiocyanate [ AITC] against N -nitrosodiethylamine induced
    experimental liver carcinogenesis, Journal of Pharmacy Research. 4-(10).
  • S. Gowtham Kumar, V.Ramakrishnan, N.Madhusudhanan, G.Thiyagarajan,
    K.Langeswaran, and M.P. Balasubramanian. 2011. p53 and caspase 3 gene expression
    potential of allyl isothiocyanate evaluated on human hepatoma cell line (HepG2). International
    journal of biological & pharmaceutical research. 2(1); 19 – 26.
  • Ramakrishnan V, Gowtham kumar S and Madhusudhanan. Nov- 2011. N Genetic basis of
    coronary artery disease and its risk factors, Journal of Pharmacy Research.
  • Madhusudhanan N, Lakshmi T, Gowtham Kumar S ,Ramakrishanan,Venu Gopala Rao Konda,
    Anitha Roy and Geetha R.V. Jul-Sep 2011.“ Invitro Antioxidant And Free Radical Scavenging
    Activity Of Aqueous And Ethanolic Flower Extract Of Nymphaea Alba ” , Int. J. Drug Dev. & Res.
    3(3); 252-258.
  • V.Ramakrisnan, S. Gowtham Kumar, G.Thiyagarajan N.Madhusudhanan and S Vincent.
    2011.The use of cytokinesis-block micronucleus (CBMN) assay to identify DNA damage in
    patients with coronary artery disease’ Int JMed Res. 1(2); 111-117.
  • V.Ramakrishnan, S. Gowtham Kumar, N.Madhusudhanan G.Thiyagarajan,and
    S.Govindaraju. 2011. “ Effect of 2-Deoxy- D- Glucose and Cyclophosphamide mediated
    modification of induced genetic damage in albino Mice ” International journal of biological &
    Pharmaceutical research. 131–138; Impact factor: 0. 92.
  • V.Ramakrishnan, S. Gowtham kumar and S.Govindaraju. 2011.“ Cytogenetic analysis of
    micronuclei, sister chromatid exchange and chromosomal aberrations in pan masala chewers”
    International journal of Pharma and Biosciences. 2(3); 01– 13.
  • Madhusudhanan N, Ruckmani A, Gowtham kumar S, Ramakrishnan Vand
    Balasubramanian MP. 2011. “ Invitro cytotoxic activity of berberine on human lung carcinoma
    cell line A549” Journal of Pharmacy Research.Vol 4, No 12.
  • V.Ramakrishnan, G.Thiyagarajan, S.Pulavendran, S.Gowtham Kumar, N.Madhusudhanan and S
    Vincent. 2010. ‘Study of Serum Metals and Antioxidant Enzymes in Patients with Coronary
    Artery Disease. International Journal of Genetic Engineering and Biotechnology. 1(3); 205 – 216.

Reviewer for Scientific Journals / Research Proposals

  • Journal of Applied Pharmaceutical Science (JAPS)
  • 10/05/2016 ICMR sponsored National level Seminar on “Recent Advances in Orthopaedic implants

Major Awards/Honours and Fellowships

  • UGC-SAPFellowship for meritorious students

Patents – 1

Research and Publication

Research – Major Research Areas

  • Genetic Polymorphism assiciated with disease,Angiogenesis,Applied Microbiology

Research – Clinical Trials / Funded Projects

  • Received EMR Project from DST SERB (Cost:47 Lakhs)

Research – List of Publications

  • Sindhu Varghese,S. Gowtham Kumar. APrevalence of micro albuminuria and diagnostic accuracy of urine dipstick for the screening of diabetic nephropathy in type 2 diabetes patients.  Biocatalysis and Agricultural Biotechnology 21 (2019) 101316.
  • Sindhu Varghese,S. Gowtham Kumar. Association between genetic variants of NOS3, TGF-β
    and susceptibility of diabetic nephropathy: A meta-analysis.Meta Gene 21:100573 ,April 2019.
    DOI: 10.1016/j.mgene.2019.100573
  • Identification of potential inhibitors for Penicillin binding protein (PBP) from Staphylococcus aureus. L Kulanthaivel, J Jeyaraman, A Biswas, Gowtham Kumar Subbaraj, S Santhoshkumar,Bioinformation 14 (9), 471-476.
    V. Ramakrishnan, R. S. Akram Husain, S. Gowtham Kumar. An overview of rare genetic
    disorders and recent diagnostic approaches, Saudi Journal for Health Sciences (2016) 5, 105-
    117.
  • Langeswaran K, Gowthamkumar S, Vijayaprakash S, Revathy R, Balasubramanian MP.
    Influence of limonin on Wnt signalling molecule in HepG2 cell lines. J Nat Sc Biol Med (4):126-
    33;2013. (Citation:27).
  • Kulanthaivel Langeswaran, Rajendran Revathy, Subbaraj Gowtham Kumar, Shanmugam
    Vijayaprakash, Maruthaiveeran Periyasamy Balasubramanian. Kaempferol ameliorates aflatoxin
    B1 (AFB1) induced hepatocellular carcinoma through modifying metabolizing enzymes,
    membrane bound ATPases and mitochondrial TCA cycle enzymes. Asian Pacific Journal of
    Tropical Biomedicine,S165-3S1659;2012. (Citation:15).
  • Peranandam Tamilselvan, Kulanthaivel Langeswaran, Shanmugam Vijayaprakash,
    Subbaraj Gowtham kumar,Rajendran Revathy, Maruthaiveeran Periyaswamy
    Balasubramanian. Efficiency of lycopene against reproductive and developmental toxicity of
    Bisphenol A in male Sprague Dawley rats, Biomedicine & Preventive Nutrition, 4, (4), 491-498;
    2014.
  • V Ramakrishnan, S Gowtham Kumar, Radha Pandiyan. Klinefelter Syndrome and its association
    with Male Infertility. As Pac JReprod, 3(1): 77-79; 2014 (Citation:1).
  • R.Revathy, K. Langeswaran, S. Gowtham Kumar, S.Vijayaprakash, P.Tamilselvan, M P
    Balasubramanian. Anti-infertility significance of aqueous extract of Ipomoea batatas (L.) Lam.
    against exposure of bisphenol A (BPA) promoted testicular toxicity in male Sprague Dawley rats,
    As Pac JReprod, 2(4), 263-271;2013 (Elsevier)(Citation:3).
  • JayaramanJagadeesan, Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar,
    Maruthaiveeran Periyaswamy Balasubramanian. Diosgenin exhibits beneficial efficiency on
    human mammary carcinoma cell line MCF-7 and against N- nitroso-N- methylurea (NMU)
    induced experimental mammary carcinoma. Biomedicine & Preventive Nutrition, 3(4), 381-388;
    2013 (Elsevier) (Citation:2).
  • Shanmugam Vijayaprakash, Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar, Rajendran
    Revathy, Maruthaiveeran Periyasamy Balasubramanian.Nephro-protective significance of
    kaempferol on mercuric chloride induced toxicity in Wistar albino rats. Biomedicine & Aging
    Pathology, 3;(3) 119-124; 2013 (Citation:6).
  • Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar, Srinivasan Perumal, Rajendran Revathy,
    Maruthaiveeran Periyasamy Balasubramaniam. Limonin – A citrus limonoid, establish anticancer
    potential by stabilizing lipid peroxidation and antioxidant status againstN- nitrosodiethylamine
    induced experimental hepatocellular carcinoma. Biomedicine & Preventive Nutrition, 3(2),
    165-171;2013 (Citation:5).
  • Gowtham kumar S, Ramakrishnan V,Madhusudhanan N, and Balasubramanian MP. 2011.
    Antioxidant activity of Allyl isothiocyanate [ AITC] against N -nitrosodiethylamine induced
    experimental liver carcinogenesis, Journal of Pharmacy Research. 4-(10).
  • S. Gowtham Kumar, V.Ramakrishnan, N.Madhusudhanan, G.Thiyagarajan,
    K.Langeswaran, and M.P. Balasubramanian. 2011. p53 and caspase 3 gene expression
    potential of allyl isothiocyanate evaluated on human hepatoma cell line (HepG2). International
    journal of biological & pharmaceutical research. 2(1); 19 – 26.
  • Ramakrishnan V, Gowtham kumar S and Madhusudhanan. Nov- 2011. N Genetic basis of
    coronary artery disease and its risk factors, Journal of Pharmacy Research.
  • Madhusudhanan N, Lakshmi T, Gowtham Kumar S ,Ramakrishanan,Venu Gopala Rao Konda,
    Anitha Roy and Geetha R.V. Jul-Sep 2011.“ Invitro Antioxidant And Free Radical Scavenging
    Activity Of Aqueous And Ethanolic Flower Extract Of Nymphaea Alba ” , Int. J. Drug Dev. & Res.
    3(3); 252-258.
  • V.Ramakrisnan, S. Gowtham Kumar, G.Thiyagarajan N.Madhusudhanan and S Vincent.
    2011.The use of cytokinesis-block micronucleus (CBMN) assay to identify DNA damage in
    patients with coronary artery disease’ Int JMed Res. 1(2); 111-117.
  • V.Ramakrishnan, S. Gowtham Kumar, N.Madhusudhanan G.Thiyagarajan,and
    S.Govindaraju. 2011. “ Effect of 2-Deoxy- D- Glucose and Cyclophosphamide mediated
    modification of induced genetic damage in albino Mice ” International journal of biological &
    Pharmaceutical research. 131–138; Impact factor: 0. 92.
  • V.Ramakrishnan, S. Gowtham kumar and S.Govindaraju. 2011.“ Cytogenetic analysis of
    micronuclei, sister chromatid exchange and chromosomal aberrations in pan masala chewers”
    International journal of Pharma and Biosciences. 2(3); 01– 13.
  • Madhusudhanan N, Ruckmani A, Gowtham kumar S, Ramakrishnan Vand
    Balasubramanian MP. 2011. “ Invitro cytotoxic activity of berberine on human lung carcinoma
    cell line A549” Journal of Pharmacy Research.Vol 4, No 12.
  • V.Ramakrishnan, G.Thiyagarajan, S.Pulavendran, S.Gowtham Kumar, N.Madhusudhanan and S
    Vincent. 2010. ‘Study of Serum Metals and Antioxidant Enzymes in Patients with Coronary
    Artery Disease. International Journal of Genetic Engineering and Biotechnology. 1(3); 205 – 216.

Reviewer for Scientific Journals / Research Proposals

  • Journal of Applied Pharmaceutical Science (JAPS)
Conferences - Papers presented
Awards, Achievements & Fellowships

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