Dr.S.Gowtham Kumar

Research – Major Research Areas

• Genetic Polymorphism assiciated with disease,Angiogenesis,Applied Microbiology

Research – Clinical Trials / Funded Projects

• Received EMR Project from DST SERB (Cost:47 Lakhs)

Research – List of Publications

• Sindhu Varghese,S. Gowtham Kumar. APrevalence of micro albuminuria and diagnostic accuracy of urine dipstick for the screening of diabetic nephropathy in type 2 diabetes patients.  Biocatalysis and Agricultural Biotechnology 21 (2019) 101316.
• Sindhu Varghese,S. Gowtham Kumar. Association between genetic variants of NOS3, TGF-β
  and susceptibility of diabetic nephropathy: A meta-analysis.Meta Gene 21:100573 ,April 2019.
  DOI: 10.1016/j.mgene.2019.100573
• Identification of potential inhibitors for Penicillin binding protein (PBP) from Staphylococcus aureus. L Kulanthaivel, J Jeyaraman, A Biswas, Gowtham Kumar Subbaraj, S Santhoshkumar,Bioinformation 14 (9), 471-476.
  V. Ramakrishnan, R. S. Akram Husain, S. Gowtham Kumar. An overview of rare genetic
  disorders and recent diagnostic approaches, Saudi Journal for Health Sciences (2016) 5, 105-
  117.
• Langeswaran K, Gowthamkumar S, Vijayaprakash S, Revathy R, Balasubramanian MP.
  Influence of limonin on Wnt signalling molecule in HepG2 cell lines. J Nat Sc Biol Med (4):126-
  33;2013. (Citation:27).
• Kulanthaivel Langeswaran, Rajendran Revathy, Subbaraj Gowtham Kumar, Shanmugam
  Vijayaprakash, Maruthaiveeran Periyasamy Balasubramanian. Kaempferol ameliorates aflatoxin
  B1 (AFB1) induced hepatocellular carcinoma through modifying metabolizing enzymes,
  membrane bound ATPases and mitochondrial TCA cycle enzymes. Asian Pacific Journal of
  Tropical Biomedicine,S165-3S1659;2012. (Citation:15).
• Peranandam Tamilselvan, Kulanthaivel Langeswaran, Shanmugam Vijayaprakash,
  Subbaraj Gowtham kumar,Rajendran Revathy, Maruthaiveeran Periyaswamy
  Balasubramanian. Efficiency of lycopene against reproductive and developmental toxicity of
  Bisphenol A in male Sprague Dawley rats, Biomedicine & Preventive Nutrition, 4, (4), 491-498;
  2014.
• V Ramakrishnan, S Gowtham Kumar, Radha Pandiyan. Klinefelter Syndrome and its association
  with Male Infertility. As Pac JReprod, 3(1): 77-79; 2014 (Citation:1).
• R.Revathy, K. Langeswaran, S. Gowtham Kumar, S.Vijayaprakash, P.Tamilselvan, M P
  Balasubramanian. Anti-infertility significance of aqueous extract of Ipomoea batatas (L.) Lam.
  against exposure of bisphenol A (BPA) promoted testicular toxicity in male Sprague Dawley rats,
  As Pac JReprod, 2(4), 263-271;2013 (Elsevier)(Citation:3).
• JayaramanJagadeesan, Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar,
  Maruthaiveeran Periyaswamy Balasubramanian. Diosgenin exhibits beneficial efficiency on
  human mammary carcinoma cell line MCF-7 and against N- nitroso-N- methylurea (NMU)
  induced experimental mammary carcinoma. Biomedicine & Preventive Nutrition, 3(4), 381-388;
  2013 (Elsevier) (Citation:2).
• Shanmugam Vijayaprakash, Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar, Rajendran
  Revathy, Maruthaiveeran Periyasamy Balasubramanian.Nephro-protective significance of
  kaempferol on mercuric chloride induced toxicity in Wistar albino rats. Biomedicine & Aging
  Pathology, 3;(3) 119-124; 2013 (Citation:6).
• Kulanthaivel Langeswaran, Subbaraj Gowtham Kumar, Srinivasan Perumal, Rajendran Revathy,
  Maruthaiveeran Periyasamy Balasubramaniam. Limonin – A citrus limonoid, establish anticancer
  potential by stabilizing lipid peroxidation and antioxidant status againstN- nitrosodiethylamine
  induced experimental hepatocellular carcinoma. Biomedicine & Preventive Nutrition, 3(2),
  165-171;2013 (Citation:5).
• Gowtham kumar S, Ramakrishnan V,Madhusudhanan N, and Balasubramanian MP. 2011.
  Antioxidant activity of Allyl isothiocyanate [ AITC] against N -nitrosodiethylamine induced
  experimental liver carcinogenesis, Journal of Pharmacy Research. 4-(10).
• S. Gowtham Kumar, V.Ramakrishnan, N.Madhusudhanan, G.Thiyagarajan,
  K.Langeswaran, and M.P. Balasubramanian. 2011. p53 and caspase 3 gene expression
  potential of allyl isothiocyanate evaluated on human hepatoma cell line (HepG2). International
  journal of biological & pharmaceutical research. 2(1); 19 – 26.
• Ramakrishnan V, Gowtham kumar S and Madhusudhanan. Nov- 2011. N Genetic basis of
  coronary artery disease and its risk factors, Journal of Pharmacy Research.
• Madhusudhanan N, Lakshmi T, Gowtham Kumar S ,Ramakrishanan,Venu Gopala Rao Konda,
  Anitha Roy and Geetha R.V. Jul-Sep 2011.“ Invitro Antioxidant And Free Radical Scavenging
  Activity Of Aqueous And Ethanolic Flower Extract Of Nymphaea Alba ” , Int. J. Drug Dev. & Res.
  3(3); 252-258.
• V.Ramakrisnan, S. Gowtham Kumar, G.Thiyagarajan N.Madhusudhanan and S Vincent.
  2011.The use of cytokinesis-block micronucleus (CBMN) assay to identify DNA damage in
  patients with coronary artery disease’ Int JMed Res. 1(2); 111-117.
• V.Ramakrishnan, S. Gowtham Kumar, N.Madhusudhanan G.Thiyagarajan,and
  S.Govindaraju. 2011. “ Effect of 2-Deoxy- D- Glucose and Cyclophosphamide mediated
  modification of induced genetic damage in albino Mice ” International journal of biological &
  Pharmaceutical research. 131–138; Impact factor: 0. 92.
• V.Ramakrishnan, S. Gowtham kumar and S.Govindaraju. 2011.“ Cytogenetic analysis of
  micronuclei, sister chromatid exchange and chromosomal aberrations in pan masala chewers”
  International journal of Pharma and Biosciences. 2(3); 01– 13.
• Madhusudhanan N, Ruckmani A, Gowtham kumar S, Ramakrishnan Vand
  Balasubramanian MP. 2011. “ Invitro cytotoxic activity of berberine on human lung carcinoma
  cell line A549” Journal of Pharmacy Research.Vol 4, No 12.
• V.Ramakrishnan, G.Thiyagarajan, S.Pulavendran, S.Gowtham Kumar, N.Madhusudhanan and S
  Vincent. 2010. ‘Study of Serum Metals and Antioxidant Enzymes in Patients with Coronary
  Artery Disease. International Journal of Genetic Engineering and Biotechnology. 1(3); 205 – 216.

Reviewer for Scientific Journals / Research Proposals

• Journal of Applied Pharmaceutical Science (JAPS)