Professional Details

Work Experience: 10 years after PhD

Membership: Parkinson's Disease Society of India, Bioinformatics society of India, Artificial intelligence society, International EECP society of Cardiology.

Orcid ID: 0000-0002-9307-5428

Books Authored: 1. Ramakrishnan V, Shiek S. S. J. Ahmed (2013) Genetic Associations with Coronary Artery Disease. LAP Lambert Academic Publishing (ISBN 978-3-659- 34060-4). 2. Alexandar, V; Saravanan, R; Ahmed, Shiek SSJ; Marine Informatics: A New Area of Research in Biology.Marine OMICS(2016):441-460.

Examinership: 6years

Contact Details

Phone number: 9551741036

Email Official:

Email Personal: shiekssjahmed@gmail.com

Research – Major Research Areas

  • Translational Neuroscience/ Biomarker Discovery/Multi – Omics/Neuro-cardio informatics/Systems Biology

Research – Clinical Trials / Funded Projects

  • DBT, Govt. of India-on going

Reviewer for Scientific Journals / Research Proposals

  • Sci Report, Plos One, Molecular Neurobiology, Clin chem Acta, Biomarker, Neuromolecular medicine

Research – List of Publications

  • https://scholar.google.com/citations?user=Vo7aYpAAAAAJ&hl=en&authuser=1
  1. Ahmed, Shiek SSJ; Santosh, Winkins; Kumar, Suresh; Christlet, Hema T Thanka; Metabolic profiling of Parkinson’s disease: evidence of biomarker from gene expression analysis and rapid neural network detection.Journal of biomedical science(2009)16:63
  2. Ahmed, Shiek SSJ; Santosh, Winkins; Kumar, Suresh; Christlet, T Hema Thanka; Neural network algorithm for the early detection of Parkinson’s disease from blood plasma by FTIR micro-spectroscopy.Vibrational Spectroscopy(2010)53:181-188
  3. Ahmed, Shiek SSJ; Ahameethunisa, A; Santosh, Winkins; QSAR and pharmacophore modeling of 4-arylthieno [3, 2-D] pyrimidine derivatives against adenosine receptor of parkinson’s disease.Journal of Theoretical and Computational Chemistry(2010)9:975-991
  4. Hemamalini, G; Ragunath, PK; Anusha, D; Magesh, KT; Ahmed, Sheik Fareeth; Relevance of gene signatures in differential diagnosis of mantle cell and B-cell chronic lymphocytic lymphoma.SRM Journal of Research in Dental Sciences(2010)1:220
  5. Ahmed, Shiek SSJ; Santosh, Winkins; Metallomic profiling and linkage map analysis of early Parkinson’s disease: a new insight to aluminum marker for the possible diagnosis.PloS one(2010)5:e11252
  6. Ahmed, Shiek SSJ; Ahameethunisa, Abdul R; Santosh, Winkins; Chakravarthy, Srinivasa; Kumar, Suresh; Systems biological approach on neurological disorders: a novel molecular connectivity to aging and psychiatric diseases.BMC systems biology(2011)5:6
  7. Ragunath, PK; Chitra, R; Mohammad, Shiek; Abhinand, PA; A systems biological study on the comorbidity of autism spectrum disorders and bipolar disorder.Bioinformation(2011)7:102
  8. Ragunath, PK; Reddy, B Vanaja; Abhinand, PA; Ahmed, Shiek SSJ; Relevance of systems biological approach in the differential diagnosis of invasive lobular carcinoma & invasive ductal carcinoma.Bioinformation(2012)8:359
  9. Ahmed, Shiek SSJ; Ramakrishnan, V; Systems biological approach of molecular descriptors connectivity: optimal descriptors for oral bioavailability prediction.PloS one(2012)7:e40654
  10. Ahmed, Shiek SSJ; Systems biology in unruptured intracranial aneurysm: a metabolomics study in serum for the detection of biomarkers.Metabolomics(2014)10:52-62
  11. Kamath, Manjunath Srinivas; Ahmed, Shiek SSJ; Dhanasekaran, M; Santosh, S Winkins; Polycaprolactone scaffold engineered for sustained release of resveratrol: therapeutic enhancement in bone tissue engineering.International journal of nanomedicine(2014)9:183
  12. Thangam, Berla; Ahmed, Shiek SSJ; A systems biological approach reveals multiple crosstalk mechanism between gram-positive and negative bacterial infections: An insight into core mechanism and unique molecular signatures.PloS one(2014)9:e89993
  13. Kumar, Suresh; Ahmed, Shiek; Santosh, Winkins; Novel markers in the early detection of Parkinson’s disease: Would serum elemental analysis work?.Movement Disorders(2014)29:
  14. Kamath, MS; Ahmed, SSSJ; Dhanasekaran, M; Santosh, SW; Bone regeneration based on tissue engineering conceptions–a 21st century perspective.Int J Nanomed(2014)1:183-195
  15. Alexandar, V; Nayar, Pradeep G; Murugesan, R; Mary, Beaulah; Darshana, P; Ahmed, Shiek SSJ; CardioGenBase: a literature based multi-omics database for major cardiovascular diseases.PloS one(2015)10:e0143188
  16. Alexandar, V; Nayar, Pradeep G; Murugesan, R; Shajahan, S; Krishnan, Jayalakshmi; Ahmed, Shiek SSJ; A systems biology and proteomics-based approach identifies SRC and VEGFA as biomarkers in risk factor mediated coronary heart disease.Molecular BioSystems(2016)12:2594-2604
  17. Ahmed, Shiek SSJ; Husain, RS Akram; Kumar, Suresh; Ramakrishnan, V; Association between MDR1 gene polymorphisms and Parkinson’s disease in Asian and Caucasian populations: a meta-analysis.Journal of the neurological sciences(2016)368:255-262
  18. Jayakumar, Vasanthi; Ahmed, Shiek SSJ; Ebenezar, Kesavarao Kumar; Multivariate analysis and molecular interaction of curcumin with PPARγ in high fructose diet induced insulin resistance in rats.SpringerPlus(2016)5:1732
  19. Ramakrishnan, V; Alphonsa, T Alu; Husain, RS Akram; Ahmed, Shiek SSJ; Subramaniyan, K; Kumar, Suresh; Association of rs1801582 and rs1801334 PARK2 polymorphisms with risk of Parkinson’s disease: a case-control study in South India and meta-analysis.Meta Gene(2016)10:32-38
  20. Sanyal, Jaya; Ahmed, Shiek SSJ; Ng, Hon Keung Tony; Naiya, Tufan; Ghosh, Epsita; Banerjee, Tapas Kumar; Lakshmi, Jaya; Guha, Gautam; Rao, Vadlamudi Raghavendra; Metallomic Biomarkers in Cerebrospinal fluid and Serum in patients with Parkinson’s disease in Indian population.Scientific reports(2016)6:35097
  21. Ramakrishnan, V; Husain, RS Akram; Ahmed, Shiek SSJ; Genetic predisposition of IL-10 promoter polymorphisms with risk of multiple sclerosis: a meta-analysis.Journal of neuroimmunology(2017)306:43405
  22. Ahmed, Shiek SSJ; Husain, RS Akram; Kumar, Suresh; Ramakrishnan, V; Association between NOS1 gene polymorphisms and schizophrenia in Asian and Caucasian populations: a meta-analysis.Neuromolecular medicine(2017)19:452-461
  23. Ramakrishnan, V; Husain, RS Akram; Ahmed, Shiek SSJ; PSEN1 gene polymorphisms in Caucasian Alzheimer’s disease: A meta-analysis.Clinica Chimica Acta(2017)473:65-70
  24. Shanmuganathan, Aruna; Krishnaveni, R; Narasimhan, Meenakshi; Viswambhar, V; Ragulan, R; Ganga, Nisha; Gangaiamaran, M; Ahmed, SSJ Shiek Fareeth; Evaluation of Peak Expiratory Flow Rate in Pregnancy in a South Indian Tertiary Care Centre.International Archives of(2017):
  25. Husain, RS Akram; Rajakeerthana, R; Sreevalsan, Anoop; Jayaprasad, P Prema; Ahmed, Shiek SSJ; Ramakrishnan, V; Prevalence of human papilloma virus with risk of cervical cancer among south Indian women: A genotypic study with meta-analysis and molecular dynamics of HPV E6 oncoprotein.Infection, Genetics and Evolution(2018)62:130-140
  26. Viji, D; Aswathi, P; Charmine, P Pricilla; Husain, RS Akram; Ameen, S Noorul; Ahmed, Shiek SSJ; Ramakrishnan, V; Genetic association of ABCC8 rs757110 polymorphism with Type 2 Diabetes Mellitus risk: A case-control study in South India and a meta-analysis.Gene Reports(2018)13:220-228
  27. Husain, RS Akram; Subramaniyan, K; Ahmed, Shiek SSJ; Ramakrishnan, V; Association of PSEN1 rs165932 polymorphism with Alzheimer’s disease susceptibility: An extensive meta-analysis.Meta Gene(2019)19:123-133
  28. Lite, Christy; Ahmed, Sheik SSJ; Santosh, Winkins; Seetharaman, Barathi; Prenatal exposure to bisphenol‐A altered miRNA‐224 and protein expression of aromatase in ovarian granulosa cells concomitant with elevated serum estradiol levels in F1 adult offspring.Journal of biochemical and molecular toxicology(2019)33:e22317
  29. Gnanakkumaar, Perumal; Murugesan, Ram; Ahmed, Shiek SSJ; Gene Regulatory Networks in Peripheral Mononuclear Cells Reveals Critical Regulatory Modules and Regulators of Multiple Sclerosis.Scientific reports(2019)9:
  30. Sanyal, Jaya; Anirudhan, Athira; Banerjee, Tapas Kumar; Guha, Gautam; Veerabathiran, Ramakrishnan; Murugesan, Ram; Ahmed, SSJ Shiek; Rao, Vadlamudi Raghavendra; PARK2 and PARK7 Gene Polymorphisms as Risk Factors Associated with Serum Element Concentrations and Clinical Symptoms of Parkinson’s Disease.Cellular and molecular neurobiology(2019):43770

Research Topics

  • Area of Specializations: Translational Multi-omics Research:
    BIOMARKER DISCOVERY, MEDICAL INFORMATICS & DATA MINING,  DRUG DISCROVERY, SYSTEMS BIOLOGY, MULTI-OMICS (TRANSCRIPTOMICS/  PROTEOMICS/ METABOLOMICS /  METALLOMICS),  ANTIRIFCIAL INTELLIGENCE/ NEXT GENERATION SEQUENING /MICROARRAYt TECHNOLOGY.
  • 15 presented/18 poster/4 Resourse person

Major Awards/Honours and Fellowships

  • CSIR-SRF/CSIR-RA/IITM-PostDoctoral Award

Achievements

  • IITM-PostDoctoral Award

Patents

  1. “System and Process For Nitric oxide estimation in fluids ”,Indian Patent Application No. 5414/CHE/2015.
  2. Method and non-invasive process for screening of coronary artery disease using Fourier Transform Infrared Spectroscopy. 201941026208
  3. Method and process for the detection of metal induced toxicity based on Fourier Transform infrared spectroscopy 201941026204
  4. Indian Copyright Reg. of : Computer Software : “CardioGenBase, a multi-omic database and information retrieval system for cardiovascular diseases” Diary Number: 11174/2015-CO/SW.
Research and Publication

Research – Major Research Areas

  • Translational Neuroscience/ Biomarker Discovery/Multi – Omics/Neuro-cardio informatics/Systems Biology

Research – Clinical Trials / Funded Projects

  • DBT, Govt. of India-on going

Reviewer for Scientific Journals / Research Proposals

  • Sci Report, Plos One, Molecular Neurobiology, Clin chem Acta, Biomarker, Neuromolecular medicine

Research – List of Publications

  • https://scholar.google.com/citations?user=Vo7aYpAAAAAJ&hl=en&authuser=1
  1. Ahmed, Shiek SSJ; Santosh, Winkins; Kumar, Suresh; Christlet, Hema T Thanka; Metabolic profiling of Parkinson’s disease: evidence of biomarker from gene expression analysis and rapid neural network detection.Journal of biomedical science(2009)16:63
  2. Ahmed, Shiek SSJ; Santosh, Winkins; Kumar, Suresh; Christlet, T Hema Thanka; Neural network algorithm for the early detection of Parkinson’s disease from blood plasma by FTIR micro-spectroscopy.Vibrational Spectroscopy(2010)53:181-188
  3. Ahmed, Shiek SSJ; Ahameethunisa, A; Santosh, Winkins; QSAR and pharmacophore modeling of 4-arylthieno [3, 2-D] pyrimidine derivatives against adenosine receptor of parkinson’s disease.Journal of Theoretical and Computational Chemistry(2010)9:975-991
  4. Hemamalini, G; Ragunath, PK; Anusha, D; Magesh, KT; Ahmed, Sheik Fareeth; Relevance of gene signatures in differential diagnosis of mantle cell and B-cell chronic lymphocytic lymphoma.SRM Journal of Research in Dental Sciences(2010)1:220
  5. Ahmed, Shiek SSJ; Santosh, Winkins; Metallomic profiling and linkage map analysis of early Parkinson’s disease: a new insight to aluminum marker for the possible diagnosis.PloS one(2010)5:e11252
  6. Ahmed, Shiek SSJ; Ahameethunisa, Abdul R; Santosh, Winkins; Chakravarthy, Srinivasa; Kumar, Suresh; Systems biological approach on neurological disorders: a novel molecular connectivity to aging and psychiatric diseases.BMC systems biology(2011)5:6
  7. Ragunath, PK; Chitra, R; Mohammad, Shiek; Abhinand, PA; A systems biological study on the comorbidity of autism spectrum disorders and bipolar disorder.Bioinformation(2011)7:102
  8. Ragunath, PK; Reddy, B Vanaja; Abhinand, PA; Ahmed, Shiek SSJ; Relevance of systems biological approach in the differential diagnosis of invasive lobular carcinoma & invasive ductal carcinoma.Bioinformation(2012)8:359
  9. Ahmed, Shiek SSJ; Ramakrishnan, V; Systems biological approach of molecular descriptors connectivity: optimal descriptors for oral bioavailability prediction.PloS one(2012)7:e40654
  10. Ahmed, Shiek SSJ; Systems biology in unruptured intracranial aneurysm: a metabolomics study in serum for the detection of biomarkers.Metabolomics(2014)10:52-62
  11. Kamath, Manjunath Srinivas; Ahmed, Shiek SSJ; Dhanasekaran, M; Santosh, S Winkins; Polycaprolactone scaffold engineered for sustained release of resveratrol: therapeutic enhancement in bone tissue engineering.International journal of nanomedicine(2014)9:183
  12. Thangam, Berla; Ahmed, Shiek SSJ; A systems biological approach reveals multiple crosstalk mechanism between gram-positive and negative bacterial infections: An insight into core mechanism and unique molecular signatures.PloS one(2014)9:e89993
  13. Kumar, Suresh; Ahmed, Shiek; Santosh, Winkins; Novel markers in the early detection of Parkinson’s disease: Would serum elemental analysis work?.Movement Disorders(2014)29:
  14. Kamath, MS; Ahmed, SSSJ; Dhanasekaran, M; Santosh, SW; Bone regeneration based on tissue engineering conceptions–a 21st century perspective.Int J Nanomed(2014)1:183-195
  15. Alexandar, V; Nayar, Pradeep G; Murugesan, R; Mary, Beaulah; Darshana, P; Ahmed, Shiek SSJ; CardioGenBase: a literature based multi-omics database for major cardiovascular diseases.PloS one(2015)10:e0143188
  16. Alexandar, V; Nayar, Pradeep G; Murugesan, R; Shajahan, S; Krishnan, Jayalakshmi; Ahmed, Shiek SSJ; A systems biology and proteomics-based approach identifies SRC and VEGFA as biomarkers in risk factor mediated coronary heart disease.Molecular BioSystems(2016)12:2594-2604
  17. Ahmed, Shiek SSJ; Husain, RS Akram; Kumar, Suresh; Ramakrishnan, V; Association between MDR1 gene polymorphisms and Parkinson’s disease in Asian and Caucasian populations: a meta-analysis.Journal of the neurological sciences(2016)368:255-262
  18. Jayakumar, Vasanthi; Ahmed, Shiek SSJ; Ebenezar, Kesavarao Kumar; Multivariate analysis and molecular interaction of curcumin with PPARγ in high fructose diet induced insulin resistance in rats.SpringerPlus(2016)5:1732
  19. Ramakrishnan, V; Alphonsa, T Alu; Husain, RS Akram; Ahmed, Shiek SSJ; Subramaniyan, K; Kumar, Suresh; Association of rs1801582 and rs1801334 PARK2 polymorphisms with risk of Parkinson’s disease: a case-control study in South India and meta-analysis.Meta Gene(2016)10:32-38
  20. Sanyal, Jaya; Ahmed, Shiek SSJ; Ng, Hon Keung Tony; Naiya, Tufan; Ghosh, Epsita; Banerjee, Tapas Kumar; Lakshmi, Jaya; Guha, Gautam; Rao, Vadlamudi Raghavendra; Metallomic Biomarkers in Cerebrospinal fluid and Serum in patients with Parkinson’s disease in Indian population.Scientific reports(2016)6:35097
  21. Ramakrishnan, V; Husain, RS Akram; Ahmed, Shiek SSJ; Genetic predisposition of IL-10 promoter polymorphisms with risk of multiple sclerosis: a meta-analysis.Journal of neuroimmunology(2017)306:43405
  22. Ahmed, Shiek SSJ; Husain, RS Akram; Kumar, Suresh; Ramakrishnan, V; Association between NOS1 gene polymorphisms and schizophrenia in Asian and Caucasian populations: a meta-analysis.Neuromolecular medicine(2017)19:452-461
  23. Ramakrishnan, V; Husain, RS Akram; Ahmed, Shiek SSJ; PSEN1 gene polymorphisms in Caucasian Alzheimer’s disease: A meta-analysis.Clinica Chimica Acta(2017)473:65-70
  24. Shanmuganathan, Aruna; Krishnaveni, R; Narasimhan, Meenakshi; Viswambhar, V; Ragulan, R; Ganga, Nisha; Gangaiamaran, M; Ahmed, SSJ Shiek Fareeth; Evaluation of Peak Expiratory Flow Rate in Pregnancy in a South Indian Tertiary Care Centre.International Archives of(2017):
  25. Husain, RS Akram; Rajakeerthana, R; Sreevalsan, Anoop; Jayaprasad, P Prema; Ahmed, Shiek SSJ; Ramakrishnan, V; Prevalence of human papilloma virus with risk of cervical cancer among south Indian women: A genotypic study with meta-analysis and molecular dynamics of HPV E6 oncoprotein.Infection, Genetics and Evolution(2018)62:130-140
  26. Viji, D; Aswathi, P; Charmine, P Pricilla; Husain, RS Akram; Ameen, S Noorul; Ahmed, Shiek SSJ; Ramakrishnan, V; Genetic association of ABCC8 rs757110 polymorphism with Type 2 Diabetes Mellitus risk: A case-control study in South India and a meta-analysis.Gene Reports(2018)13:220-228
  27. Husain, RS Akram; Subramaniyan, K; Ahmed, Shiek SSJ; Ramakrishnan, V; Association of PSEN1 rs165932 polymorphism with Alzheimer’s disease susceptibility: An extensive meta-analysis.Meta Gene(2019)19:123-133
  28. Lite, Christy; Ahmed, Sheik SSJ; Santosh, Winkins; Seetharaman, Barathi; Prenatal exposure to bisphenol‐A altered miRNA‐224 and protein expression of aromatase in ovarian granulosa cells concomitant with elevated serum estradiol levels in F1 adult offspring.Journal of biochemical and molecular toxicology(2019)33:e22317
  29. Gnanakkumaar, Perumal; Murugesan, Ram; Ahmed, Shiek SSJ; Gene Regulatory Networks in Peripheral Mononuclear Cells Reveals Critical Regulatory Modules and Regulators of Multiple Sclerosis.Scientific reports(2019)9:
  30. Sanyal, Jaya; Anirudhan, Athira; Banerjee, Tapas Kumar; Guha, Gautam; Veerabathiran, Ramakrishnan; Murugesan, Ram; Ahmed, SSJ Shiek; Rao, Vadlamudi Raghavendra; PARK2 and PARK7 Gene Polymorphisms as Risk Factors Associated with Serum Element Concentrations and Clinical Symptoms of Parkinson’s Disease.Cellular and molecular neurobiology(2019):43770

Research Topics

  • Area of Specializations: Translational Multi-omics Research:
    BIOMARKER DISCOVERY, MEDICAL INFORMATICS & DATA MINING,  DRUG DISCROVERY, SYSTEMS BIOLOGY, MULTI-OMICS (TRANSCRIPTOMICS/  PROTEOMICS/ METABOLOMICS /  METALLOMICS),  ANTIRIFCIAL INTELLIGENCE/ NEXT GENERATION SEQUENING /MICROARRAYt TECHNOLOGY.
Conferences - Papers presented
Awards, Achievements & Fellowships

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