Dr. Shiek Fareeth Ahmed

Research – Major Research Areas

• Translational Neuroscience/ Biomarker Discovery/Multi – Omics/Neuro-cardio informatics/Systems Biology

Research – Clinical Trials / Funded Projects

• DBT, Govt. of India-on going

Reviewer for Scientific Journals / Research Proposals

• Sci Report, Plos One, Molecular Neurobiology, Clin chem Acta, Biomarker, Neuromolecular medicine

Research – List of Publications

• https://scholar.google.com/citations?user=Vo7aYpAAAAAJ&hl=en&authuser=1

1. Ahmed, Shiek SSJ; Santosh, Winkins; Kumar, Suresh; Christlet, Hema T Thanka; Metabolic profiling of Parkinson’s disease: evidence of biomarker from gene expression analysis and rapid neural network detection.Journal of biomedical science(2009)16:63
2. Ahmed, Shiek SSJ; Santosh, Winkins; Kumar, Suresh; Christlet, T Hema Thanka; Neural network algorithm for the early detection of Parkinson’s disease from blood plasma by FTIR micro-spectroscopy.Vibrational Spectroscopy(2010)53:181-188
3. Ahmed, Shiek SSJ; Ahameethunisa, A; Santosh, Winkins; QSAR and pharmacophore modeling of 4-arylthieno [3, 2-D] pyrimidine derivatives against adenosine receptor of parkinson’s disease.Journal of Theoretical and Computational Chemistry(2010)9:975-991
4. Hemamalini, G; Ragunath, PK; Anusha, D; Magesh, KT; Ahmed, Sheik Fareeth; Relevance of gene signatures in differential diagnosis of mantle cell and B-cell chronic lymphocytic lymphoma.SRM Journal of Research in Dental Sciences(2010)1:220
5. Ahmed, Shiek SSJ; Santosh, Winkins; Metallomic profiling and linkage map analysis of early Parkinson’s disease: a new insight to aluminum marker for the possible diagnosis.PloS one(2010)5:e11252
6. Ahmed, Shiek SSJ; Ahameethunisa, Abdul R; Santosh, Winkins; Chakravarthy, Srinivasa; Kumar, Suresh; Systems biological approach on neurological disorders: a novel molecular connectivity to aging and psychiatric diseases.BMC systems biology(2011)5:6
7. Ragunath, PK; Chitra, R; Mohammad, Shiek; Abhinand, PA; A systems biological study on the comorbidity of autism spectrum disorders and bipolar disorder.Bioinformation(2011)7:102
8. Ragunath, PK; Reddy, B Vanaja; Abhinand, PA; Ahmed, Shiek SSJ; Relevance of systems biological approach in the differential diagnosis of invasive lobular carcinoma & invasive ductal carcinoma.Bioinformation(2012)8:359
9. Ahmed, Shiek SSJ; Ramakrishnan, V; Systems biological approach of molecular descriptors connectivity: optimal descriptors for oral bioavailability prediction.PloS one(2012)7:e40654
10. Ahmed, Shiek SSJ; Systems biology in unruptured intracranial aneurysm: a metabolomics study in serum for the detection of biomarkers.Metabolomics(2014)10:52-62
11. Kamath, Manjunath Srinivas; Ahmed, Shiek SSJ; Dhanasekaran, M; Santosh, S Winkins; Polycaprolactone scaffold engineered for sustained release of resveratrol: therapeutic enhancement in bone tissue engineering.International journal of nanomedicine(2014)9:183
12. Thangam, Berla; Ahmed, Shiek SSJ; A systems biological approach reveals multiple crosstalk mechanism between gram-positive and negative bacterial infections: An insight into core mechanism and unique molecular signatures.PloS one(2014)9:e89993
13. Kumar, Suresh; Ahmed, Shiek; Santosh, Winkins; Novel markers in the early detection of Parkinson’s disease: Would serum elemental analysis work?.Movement Disorders(2014)29:
14. Kamath, MS; Ahmed, SSSJ; Dhanasekaran, M; Santosh, SW; Bone regeneration based on tissue engineering conceptions–a 21st century perspective.Int J Nanomed(2014)1:183-195
15. Alexandar, V; Nayar, Pradeep G; Murugesan, R; Mary, Beaulah; Darshana, P; Ahmed, Shiek SSJ; CardioGenBase: a literature based multi-omics database for major cardiovascular diseases.PloS one(2015)10:e0143188
16. Alexandar, V; Nayar, Pradeep G; Murugesan, R; Shajahan, S; Krishnan, Jayalakshmi; Ahmed, Shiek SSJ; A systems biology and proteomics-based approach identifies SRC and VEGFA as biomarkers in risk factor mediated coronary heart disease.Molecular BioSystems(2016)12:2594-2604
17. Ahmed, Shiek SSJ; Husain, RS Akram; Kumar, Suresh; Ramakrishnan, V; Association between MDR1 gene polymorphisms and Parkinson’s disease in Asian and Caucasian populations: a meta-analysis.Journal of the neurological sciences(2016)368:255-262
18. Jayakumar, Vasanthi; Ahmed, Shiek SSJ; Ebenezar, Kesavarao Kumar; Multivariate analysis and molecular interaction of curcumin with PPARγ in high fructose diet induced insulin resistance in rats.SpringerPlus(2016)5:1732
19. Ramakrishnan, V; Alphonsa, T Alu; Husain, RS Akram; Ahmed, Shiek SSJ; Subramaniyan, K; Kumar, Suresh; Association of rs1801582 and rs1801334 PARK2 polymorphisms with risk of Parkinson’s disease: a case-control study in South India and meta-analysis.Meta Gene(2016)10:32-38
20. Sanyal, Jaya; Ahmed, Shiek SSJ; Ng, Hon Keung Tony; Naiya, Tufan; Ghosh, Epsita; Banerjee, Tapas Kumar; Lakshmi, Jaya; Guha, Gautam; Rao, Vadlamudi Raghavendra; Metallomic Biomarkers in Cerebrospinal fluid and Serum in patients with Parkinson’s disease in Indian population.Scientific reports(2016)6:35097
21. Ramakrishnan, V; Husain, RS Akram; Ahmed, Shiek SSJ; Genetic predisposition of IL-10 promoter polymorphisms with risk of multiple sclerosis: a meta-analysis.Journal of neuroimmunology(2017)306:43405
22. Ahmed, Shiek SSJ; Husain, RS Akram; Kumar, Suresh; Ramakrishnan, V; Association between NOS1 gene polymorphisms and schizophrenia in Asian and Caucasian populations: a meta-analysis.Neuromolecular medicine(2017)19:452-461
23. Ramakrishnan, V; Husain, RS Akram; Ahmed, Shiek SSJ; PSEN1 gene polymorphisms in Caucasian Alzheimer’s disease: A meta-analysis.Clinica Chimica Acta(2017)473:65-70
24. Shanmuganathan, Aruna; Krishnaveni, R; Narasimhan, Meenakshi; Viswambhar, V; Ragulan, R; Ganga, Nisha; Gangaiamaran, M; Ahmed, SSJ Shiek Fareeth; Evaluation of Peak Expiratory Flow Rate in Pregnancy in a South Indian Tertiary Care Centre.International Archives of(2017):
25. Husain, RS Akram; Rajakeerthana, R; Sreevalsan, Anoop; Jayaprasad, P Prema; Ahmed, Shiek SSJ; Ramakrishnan, V; Prevalence of human papilloma virus with risk of cervical cancer among south Indian women: A genotypic study with meta-analysis and molecular dynamics of HPV E6 oncoprotein.Infection, Genetics and Evolution(2018)62:130-140
26. Viji, D; Aswathi, P; Charmine, P Pricilla; Husain, RS Akram; Ameen, S Noorul; Ahmed, Shiek SSJ; Ramakrishnan, V; Genetic association of ABCC8 rs757110 polymorphism with Type 2 Diabetes Mellitus risk: A case-control study in South India and a meta-analysis.Gene Reports(2018)13:220-228
27. Husain, RS Akram; Subramaniyan, K; Ahmed, Shiek SSJ; Ramakrishnan, V; Association of PSEN1 rs165932 polymorphism with Alzheimer’s disease susceptibility: An extensive meta-analysis.Meta Gene(2019)19:123-133
28. Lite, Christy; Ahmed, Sheik SSJ; Santosh, Winkins; Seetharaman, Barathi; Prenatal exposure to bisphenol‐A altered miRNA‐224 and protein expression of aromatase in ovarian granulosa cells concomitant with elevated serum estradiol levels in F1 adult offspring.Journal of biochemical and molecular toxicology(2019)33:e22317
29. Gnanakkumaar, Perumal; Murugesan, Ram; Ahmed, Shiek SSJ; Gene Regulatory Networks in Peripheral Mononuclear Cells Reveals Critical Regulatory Modules and Regulators of Multiple Sclerosis.Scientific reports(2019)9:
30. Sanyal, Jaya; Anirudhan, Athira; Banerjee, Tapas Kumar; Guha, Gautam; Veerabathiran, Ramakrishnan; Murugesan, Ram; Ahmed, SSJ Shiek; Rao, Vadlamudi Raghavendra; PARK2 and PARK7 Gene Polymorphisms as Risk Factors Associated with Serum Element Concentrations and Clinical Symptoms of Parkinson’s Disease.Cellular and molecular neurobiology(2019):43770

Research Topics

• Area of Specializations: Translational Multi-omics Research:
  BIOMARKER DISCOVERY, MEDICAL INFORMATICS & DATA MINING,  DRUG DISCROVERY, SYSTEMS BIOLOGY, MULTI-OMICS (TRANSCRIPTOMICS/  PROTEOMICS/ METABOLOMICS /  METALLOMICS),  ANTIRIFCIAL INTELLIGENCE/ NEXT GENERATION SEQUENING /MICROARRAYt TECHNOLOGY.